2885 Sanford Ave, SW # 10293, Grandville, MI 49418

Clinical Proof

Over 30 clinical studies Over 20 respected medical journals One remarkable formula.

Journal: International Surgery

Anti-Inflammatory Effect of the Kampo Japanese Traditional Medicine Daikenchuto After Colorectal Resection

Journal: Journal of Gastroenterology

Daikenchuto, a traditional Japanese herbal medicine, ameliorates postoperative ileus by anti-inflammatory action through nicotinic acetylcholine receptors

Journal: Digestive Diseases and Sciences

Kampo Medicine “Dai-Kenchu-To” Prevents Bacterial Translocation in Rats

Journal: Current Therapeutic Research

Effects of Daikenchuto on Abdominal Bloating Accompanied by Chronic Constipation: A Prospective, Single-Center Randomized Open Trial

Journal: Journal of Surgical Research

Colonic vascular conductance increased by Daikenchuto via calcitonin gene-related peptide and receptor-activity modifying protein 1

Journal: The Tohoku Journal of Experimental Medicine

The herbal medicine Daikenchuto increases blood flow in the superior mesenteric artery

Journal: Hepato-gastroenterology

Influence of Dai-kenchu-to (DKT) on human portal blood flow

Journal: Journal of the Anus, Rectum and Colon

Clinical efficacy of Japanese herbal medicine daikenchuto in the management of fecal incontinence: A single-center, observational study

Journal: Journal of Evidence-Based Integrative Medicine

Traditional Japanese Medicine Daikenchuto Improves Functional Constipation in Poststroke Patients

Journal: Journal of Pharmacological Sciences

Contraction of gut smooth muscle cells assessed by fluorescence imaging

Journal: Evidence-Based Complementary and Alternative Medicine

Traditional Japanese medicine daikenchuto improves functional constipation in poststroke patients

Journal: The Cochrane database of systematic reviews

Daikenchuto for reducing postoperative ileus in patients undergoing elective abdominal surgery

Journal: European Journal of Pediatric Surgery

Effects of herbal medicine Dai-Kenchu-to on anorectal function in children with severe constipation

Journal: Journal of the Anus, Rectum and Colon

The Japanese Extracted Herbal Medicine Daikenchuto Increases the Contractile Activity of the Internal Anal Sphincter Muscle in Conscious Dogs

Journal: Journal of Crohn's and Colitis

Anti-colitis and -adhesion effects of daikenchuto via endogenous adrenomedullin enhancement in Crohn’s disease mouse model

Journal: Journal of Gastroenterology and Hepatology

Ginsenoside Rb1 promotes intestinal epithelial wound healing through extracellular signal-regulated kinase and Rho signaling

Journal: World Journal of Gastroenterology

Daikenchuto (Da-Jian-Zhong-Tang) ameliorates intestinal fibrosis by activating myofibroblast transient receptor potential ankyrin 1 channel

Journal: Nature

Growth stimulation of Bifidobacterium from human colon using daikenchuto in an in vitro model of human intestinal microbiota

Journal: Gene

Microbiome biomarkers associated with the gut contraction response elicited by the Japanese traditional medicine daikenchuto

Journal: The Journal of Medical Investigation

Effect of Kampo medicine “Dai-kenchu-to” on microbiome in the intestine of the rats with fast stress

Journal: Digestive Diseases and Sciences

Kampo medicine “Dai-kenchu-to” prevents bacterial translocation in rats

Journal: Journal of Evidence-Based Integrative Medicine

Responder Analysis of Daikenchuto Treatment for Constipation in Poststroke Patients: A Subanalysis of a Randomized Control Trial

Journal: Journal of Gastroenterology and Hepatology (JGH Open)

Daikenchuto attenuates visceral pain and suppresses eosinophil infiltration in inflammatory bowel disease in murine models

Journal: Current Therapeutic Research

Effects of Daikenchuto on Abdominal Bloating Accompanied by Chronic Constipation: A Prospective, Single-Center Randomized Open Trial

Journal: Journal of Natural Medicines

Anticancer effect of a Kampo preparation Daikenchuto

Journal: Cancer Research

GPR109A is a G-protein-coupled receptor for the bacterial fermentation product butyrate and functions as a tumor suppressor in colon

Journal: Food and Chemical Toxicology

Antioxidant effects of Panax ginseng C.A. Meyer in healthy subjects: a randomized, placebo-controlled clinical trial

Journal: Molecular and Cellular Biochemistry

Antioxidant properties of a North American ginseng extract

Journal: International Journal of Chronic Diseases & Therapy

Efficacy and Safety of Daikenchuto for Constipation and Dose-Dependent Differences in Clinical Effects

Journal: Movement Disorders - Official journal of the Movement Disorder Society

Dietary herb extract daikenchuto ameliorates constipation in parkinsonian patients

Journal: Surgery Today

The effect of traditional Japanese medicine (Kampo) on gastrointestinal function

Journal: Journal of the Anus, Rectum and Colon

Efficacy and Safety of the Japanese Herbal Medicine Daikenchuto (DKT) in Elderly Fecal Incontinence Patients: A Prospective Study

Journal: Journal of Natural Medicines

Memory and learning-enhancing effect of Daikenchuto, a traditional Japanese herbal medicine, in mice

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